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| Corporate Overview |
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Adimab is changing the discovery, maturation and production of therapeutic human antibodies. By integrating all aspects of antibody discovery and developing sophisticated screening methods, Adimab can rapidly discover high affinity antibodies that also behave well in a formulation and manufacturing context. Our proprietary library design and presentation technology allows us to discover full-length human antibodies with broad epitope coverage, high affinity and therapeutic relevance faster than any current technology.
Conventional antibody discovery is a lengthy process that involves a myriad of different technologies that need to be assembled before a commercial antibody can be produced. The integration of: (i) library design, (ii) display methodology, (iii) reformatting between different hosts and expression constructs, and (iv) GMP cell line development is resource intensive, time consuming, and typically results in extensive royalty obligations to multiple third parties.
Adimab was founded by two of the world's leading yeast biotechnologists: Professor Tillman Gerngross (Dartmouth, Co-founder of GlycoFi, Inc., a wholly owned subsidiary of Merck & Co. since 2006) who led the humanization effort to engineer yeast for the production of human glycoproteins, and Professor Dane Wittrup (MIT, Co-founder of Biodisplay, acquired by Abbott Labs in 2001.) who pioneered yeast surface display for the discovery and maturation of antibody fragments. The partnership between Wittrup and Gerngross has been viewed by many as the "Yeast Dream Team" in therapeutic antibody discovery, maturation and production. |
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