Terrance A. Stadheim, Huijuan Li, Warren Kett, Irina N Burnina and Tillman U. Gerngross. Use of high-performance anion exchange chromatography with pulsed amperometric detection for O-glycan determination in yeast. Nature Protocols 3:1026 - 1031, 2008.

Shaun M. Lippow, K. Dane Wittrup, Bruce Tidor. Computational Design of Antibody Affinity Improvement Beyond In Vivo Maturation. Nature Biotechnology 25:1171 - 1176, 2007.

A. S. Bhatt, A. Welm, C. J. Farady, M. Vasquez, K. Wilson, and C. S. Craik (2007) Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway. Proc. Natl. Acad. Sci. USA 104, 5771-5776.

Chao, G., Lau, W.L., Hackel, B.J., Sazinsky, S.L., Lippow, S.M., Wittrup, K.D. Isolating and Engineering human antibodies using yeast surface display. Nature Protocols 1:755 - 768, 2006.

Hamilton SR, et al., and Tillman U. Gerngross. Humanization of yeast to produce complex terminally sialylated glycoproteins. Science. 313(5792):1441-3. 2006

Huijuan Li, et al., and Tillman U. Gerngross. Production of humanized IgGs in the yeast Pichia pastoris and use of glycoengineered yeast cell lines to elucidate glycosylation dependent structure activity relationships. Nature Biotechnology, 2:210-215, (2006)

J.A. Rakestraw, A. R. Baskaran, K.D. Wittrup. A Flow Cytometric Assay for Screening Improved Heterologous Protein Secretion in Yeast. Biotechnology Progress, 22(4):1200-8, 2006.

Midelfort, K.S., Wittrup, K.D. Context-Dependent Mutations Predominate in an Engineered High Affinity Single Chain Antibody Fragment. Protein Science, 15(2):324-34, 2006.

Sivasubramanian A, Chao G, Pressler HM, Wittrup KD, Gray JJ. Structural Model of the mAb 806-EGFR Complex Using Computational Docking followed by Computational and Experimental Mutagenesis. Structure 14(3):401-14, 2006.

Peelle, B. R., Krauland, E. M., Wittrup, K. D., and Belcher, A. M. (2005). Probing the interface between biomolecules and inorganic materials using yeast surface display and genetic engineering. Acta Biomaterialia 1, 145-154.

Peelle, B. R., Krauland, E. M., Wittrup, K. D., and Belcher, A. M. (2005). Design criteria for engineering inorganic material-specific peptides. Langmuir, 21, 6929-6933.

Rao, BM, Lauffenburger, DA, Wittrup KD. Integrating cell-level kinetic modeling into the design of engineered protein therapeutics. Nature Biotechnology, 23(2):191-4, 2005.

Razai, A., Garcia-Rodriguez, C., Lou J., Geren, I., Forsyth, C., Robles, Y., Tsai, R., Smith, T., Smith, L., Siegel, R., Feldhaus, M., and Marks, J.D. Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A. J. Mol. Biol. 2005, Aug 5; 352(1): 158-169.

Wildt S, and Gerngross TU. The humanization of N-glycosylation pathways in yeast.
Nature Reviews Microbiology, 3(2):119-28 (2005)

Colby DW, Chu Y, Cassady JP, Duennwald M, Zazulak H, Webster JM, Messer A, Lindquist S, Ingram VM, Wittrup KD. Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. Proc Natl Acad Sci U S A. 101(51): 17616-17621, 2004.

Dawson, M., Krauland, E.M., Wirtz, D., and Hanes, J. (2004). Transport of polymeric nanoparticle gene carriers in gastric mucus. Biotechnology Progress, 20, 851-857.

T.U. Gerngross, Advances in the production of human therapeutic proteins in yeasts and filamentous fungi. Nature Biotechnology,.pp1409 -1414 (2004).

Graff, C.P., Chester K., Begent R., Wittrup, K.D. Directed Evolution of an Anti-Carcinoembryonic Antigen scFv with a Four-Day Monovalent Dissociation Half-time at 37 (C. Protein Engineering, Design & Selection, 17:293, 2004.

P.R. Hinton, M. G. Johlfs, J. M. Xiong, K. Hanestad, K. C. Ong, C. Bullock, S. Keller, M.T. Tang, J.Y. Tso, M. Vasquez, & N. Tsurushita (2004) 'Engineered Human IgG Antibodies with Longer Serum Half-lives in Primates' J. Biol. Chem. 279, 6213-6216.

Midelfort, K.S., Hernandez, H.H., Lippow, S.M., Tidor, B., Drennan, C.L., Wittrup, K.D. Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody. J. Mol. Biol., 343(3):685-701, 2004.

Siegel, R.W., J.R. Coleman, K.D. Miller, M.J. Feldhaus. High efficiency recovery and epitope-specific sorting of an scFv yeast display library. Journal of Immunologic Methods, 2004, Vol. 286: 141-153.

N. Tsurushita, M. Park, K. Pakabunto, K. Ong, A. Avdalovic, H. Fu, A. Jia, M. Vasquez & S. Kumar (2004) 'Humanization of a chicken anti-IL-12 monoclonal antibody' J. Immunol. Methods 295, 9-19.

Swers, J.S., Kellogg, B.A., Wittrup, K.D. Shuffled Antibody Libraries Created by In Vivo Homologous Recombination and Yeast Surface Display. Nucleic Acids Research. 32(3):36, 2004.

Weaver-Feldhaus, J.M., J. Lou, J.R. Coleman, R.W. Siegel, J.D. Marks, M.J. Feldhaus. Yeast mating for combinatorial Fab library generation and surface display. FEBS Letters, 2004, Vol. 564: 24-34.

Byung-Kwon Choi, Piotr Bobrowicz, Robert C. Davidson, Stephen R. Hamilton, David H. Kung, Huijuan Li, R. G. Miele, Juergen H. Nett, Stefan Wildt, and T. U. Gerngross, Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris, Proc. Natl. Acad. Sci., 100:9, 5022-27, (2003)

Feldhaus, M.J., Siegel, R.W., Opresko L.K., Coleman, J.R., Weaver Feldhaus J.M., Yeung Y.A., Cochran J.R., Heinzelman P., Colby D., Swers, J., Graff C., Wiley H.S., Wittrup K.D. Flow cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library. Nature Biotechnology, 21:163, 2003.

Stephen R. Hamilton, et al., and Tillman U. Gerngross, Production of complex human glycoproteins in yeast, Science, 301, 1244-46, (2003).

Fu, J., Fiegel, J., Krauland, E.M., and Hanes, J. (2002). New polymeric carriers for controlled drug delivery following inhalation or injection. Biomaterials 23, 4425-4433.

T. Sandrock, M. Poritz, M. Kim, M.J. Feldhaus, B. Roth, G. Caponigro, A. Kamb. expression levels of transdominant peptides and proteins in Saccharomyces cerevisiae. Yeast, 2002, Vol. 19:1-7.

Yeung, YA, Wittrup KD. Quantitative Screening of Yeast Surface-Displayed Polypeptide Libraries by Magnetic Bead Capture. Biotechnology Progress 18:212, 2002.

E.T. Boder, K.S. Midelfort, K.D. Wittrup. Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. PNAS, 97:10701, 2000.

Feldhaus, M.J., M. Lualhati, K. Cardon, B. Roth, A, Kamb. Oligonucleotide-conjugated beads for transdominant genetic experiments. Nucleic Acids Res., 2000, Vol. 28:534-543.

J. Van Antwerp, K.D. Wittrup: Fine Affinity Discrimination by Yeast Surface Display and Flow Cytometry. Biotechnology Progress 16:31-37, 2000.

M.S. Cole, K.E. Stellrecht, J.D. Shi, M. Homola, D.-H. Hsu, C. Anasetti, M. Vasquez & J. Tso (1999) 'HuM291, a Humanized anti-CD3 Antibody, is Immunosuppressive to T Cells while Exhibiting Reduced Mitogenicity In Vitro'Transplantation 68, 563-571.

E. T. Boder and K. D. Wittrup: Optimal Screening of Surface Displayed Polypeptide Libraries. Biotechnology Progress 14:55-62, 1998.

E. V. Shusta, R. T. Raines, A. Pluckthun, K. D. Wittrup: Increasing the Secretory Capacity of Saccharomyces cerevisiae for Production of Single-chain Antibody Fragments, Nature Biotechnology, 8:773-777, 1998.

E. T. Boder and K. D. Wittrup: Yeast Surface Display for Screening Combinatorial Polypeptide Libraries. Nature Biotechnology 15:553-537, 1997.

S.M. Glaser, M. Vasquez, P.W. Payne & W.P. Schneider (1992) 'Dissection of the Combining Site in a Humanized Anti-Tac Antibody' J. Immunology 149, 2607-2614.