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An evaluation of the performance of various co-folding methods for predicting antibody-antigen interactions
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Thermal pressuring of an anti-CD3 scFv in Adimab's yeast platform yields stabilizing mutations for T cell engagers
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Engineered HC–LC interfaces direct correct chain pairing, enabling high-purity multispecific antibodies
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TCR-targeting VHHs enable orthogonal T cell activation with strong cytotoxicity and species cross-reactivity
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Enabling high-purity assembly without complex purification to support rapid format exploration of multispecifics
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Systematic TCE exploration using tunable CD3/CD28 panels and rapid format screening optimizes efficacy